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Cost-effectiveness analysis of gefitinib versus chemotherapy protocols in the first line treatment of non small-cell EGFR positive lung cancer

Abstract

Introduction: Lung cancer has high incidence and mortality in Brazil. Most tumors are non small-cell (NSCLC) and 54% present with metastases at diagnosis. The aim of this study was to evaluate the cost-effectiveness of gefitinib versus chemotherapy protocols in the treatment of advanced NSCLC with EGFR mutation in the ...

Castration-resistant prostate cancer (CRPC)

Keywords

Prostate Cancer; castration resistant; hormone resistant; 

How to cite this article

Sadi, M. V., et al. (2011). Castration-resistant prostate cancer (CRPC). 25th Meeting of the Brazilian Committee of Uro-oncology Studies ...

Cost-Effectiveness and Budget Impact Analysis of Rivaroxaban in the Prevention of Thromboembolic Events in Patients Performing Hip and Knee Arthroplasty in Comparison with No Treatment Under the Brazilian Private Health Care System Perspective

Keywords

Rivaroxaban; Brazil; Thromboembolism/ drug therapy; private health system; health insurance companies; hip and knee surgery; 

How to cite this article

Schiola, A., et al. (2011). "Cost-Effectiveness and ...

Update 2011: Budget Impact Analysis and Cost-Effectiveness of Rivaroxaban in the Prevention of Thromboembolic Events in Patients Performing Hip and Knee Arthroplasty in Comparison with Dabigatran Under the Brazilian Private Health Care System Perspective

Keyword

Rivaroxaban; cost effectiveness analysis; budgetary impact; Thromboembolism/ drug therapy; dabigatran; Brazil; private health system; health insurance companies; 

How to cite this article

Schiola, ...

Update 2011: Cost-Effectiveness and Budget Impact Analysis of Rivaroxaban in the Prevention of Thromboembolic Events in Patients Performing Hip and Knee Arthroplasty in Comparison With Enoxaparin Under the Brazilian Private Health Care System Perspective

Abstract

Objectives: To develop a cost-effectiveness and a budget impact analysis of Rivaroxaban in the prevention of thromboembolic events in patients performing hip and knee arthroplasty in comparison with Enoxaparin under the Brazilian private health care system perspective. Methods: A decision tree analysis was ...

Intra Muscular Testosterone Undecanoate (TU) (NEBIDO®) as Testosterone Replacement Therapy (TRT) for Androgen Deficiency in the Aging Male (ADAM) and Diabetes Mellitus Type 2 (DM2) Patients: Brazilian Economic Modeling

Abstract

Objectives: To determine the cost-effectiveness of TRT with TU (NEBIDO®) compared with placebo for patients with ADAM and DM2, from the Brazilian Private Healthcare System perspective. Methods: The study was a cost-effectiveness analysis based on Markov modeling to estimate costs and consequences of ...

Antibiotic prophylaxis for transrectal prostate biopsy

Abstract

BACKGROUND: Transrectal prostate biopsy (TRPB) is a well established procedure used to obtain tissue for the histological diagnosis of carcinoma of the prostate. Despite the fact that TRPB is generally considered a safe procedure, it may be accompanied by traumatic and infective complications, including asymptomatic ...

Real World Data On Multiple Myeloma (MM) Treatment In Brazil: Guidance For The Private Health Care System (PHS)

Abstract

OBJECTIVES: New treatments in oncology frequently imply in higher costs. Histori- cally there is a lack of statistical data on cancer treatments in PHS in Brazil. Higher costs combined to lack of information may result in waste of resources. We present here real world data (RWD) on MM treatment collected from a dedicated database of cancer ...

Efficacy And Cardiac Safety Of Trastuzumab (T) In The Adjuvant Treatment Of Her2-Positive Early-Stage Breast Cancer: A Systematic Review (SR) And Meta-Analysis (MA)

Abstract

OBJECTIVES: Trastuzumab (T) is now part of the standard adjuvant treatment for HER2 positive, breast cancer patients. However, the results of the studies are not uniform and there are still doubts about the ideal indication and schedule for its use. Our objective was to perform a systematic review (SR) and meta-analysis (MA) of all randomized ...

Efficacy Of The Combination Bevacizumab Plus Chemotherapy (BEV-CT) Compared To Ct Alone In Previously Untreated Locally Advanced Or Metastatic Non-Small Cell Lung Cancer (NSCLC): Systematic Review (SR) And Meta-Analysis (MA)

Abstract

OBJECTIVES: To perform SR with MA of all randomized controlled trials (RCT) comparing the efficacy of BEV-CT versus CT alone in previously untreated locally advanced or metastatic NSCLC. METHODS: We searched MEDLINE, EMBASE, LILACS, and CENTRAL among others. Primary end points were overall survival (OS) and progression-free survival (PFS). Adverse ...