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Cost analysis of insulin degludec in comparison with insulin glargine u100 in the treatment of type 1 diabetes mellitus in the Brazilian public health care system

Abstract

OBJECTIVES: To evaluate direct costs of the use of insulin degludec (IDeg) in comparison to insulin glargine U100 (IGlar) in the treatment of Type 1 Diabetes Mellitus patients in a basal-bolus regimen (T1DMB/B) in the Brazilian public healthcare system. METHODS: A one-year short-term model was developed to evaluate ...

Economic impact of dengue tourism in Brazil

Abstract

Introduction: Dengue is an endemic disease that is rapidly growing worldwide. A recent study estimates that 390 million annual infections occur around the world. Dengue has become one of the major diseases affecting the Brazilian public health.1 The rising incidence of the disease and its unpredictable outbreaks result ...

Amino acid formula as a new strategy for diagnosing cow s milk allergy in infants: is it cost-effective?

Abstract

OBJECTIVE: To estimate the cost-effectiveness of a new strategy that uses an amino acid formula in the elimination diet of infants with suspected cow's milk allergy (CMA). METHODS: This pharmacoeconomic study was developed from the perspective of the Brazilian Public Healthcare System. The new strategy proposes using an amino acid formula in the ...

Government reimbursement values versus real chemotherapy costs in the Brazilian public health care system: another barrier to treatment access?

Abstract

OBJECTIVES:   Cancer therapy reimbursements in the Brazilian Public Healthcare System (SUS) are controlled by the Authorization for High Complexity Procedures (APAC) system. Each treatment-line has a specific code/reimbursement value that should cover a month of therapy. We aimed to compare real chemotherapy costs ...

Patient safety: an overview of the hospital accreditation process in Brazil

Abstract

OBJECTIVES: Patient safety (PS) is a serious public health issue worldwide. Estimates show that 1 in 10 patients are harmed while receiving hospital care due to errors or adverse events. Although literature is controversial on the impact of hospital accreditation (HA) on quality-of-care issues, it continues to grow globally. ...

Improving patient safety through communication: a Brazilian perspective

Abstract

OBJECTIVES: Ineffective communication among healthcare professionals is one of the leading causes of medical errors and patient harm. Several studies have shown that communication failures were implicated at the root of over 70% of sentinel events. Also, in the acute care setting, communication failures lead to increases in ...

Efficacy and safety of bevacizumab plus chemotherapy compared to chemotherapy alone in previously untreated advanced or metastatic colorectal cancer: a systematic review and meta-analysis

Abstract

Colorectal cancer (CRC) is the fourth most frequently diagnosed cancer and the second leading cause of neoplasm-related death in the United States. Several studies analyzed the efficacy of bevacizumab combined with different chemotherapy regimens consisting on drugs such as 5-FU, capecitabine, irinotecan and oxaliplatin. ...

Pharmacovigilance in Oncology: Knowledge and Perception on Adverse Events Reporting in Brazil

Abstract

Introduction: Pharmacovigilance represents an important tool to support the maintenance of drug safety through evaluation of spontaneous adverse events (AE) reporting. Oncoguia is an independent non-profit institution, with the mission of helping cancer patients to live better. The present study can contribute to identify barriers on AE ...

Impact of Indiscriminate Use of Pump Infusion Sets (PIS) on the Cost of Chemotherapy Treatments: a Cost-Minimization Study

Abstract

OBJECTIVES: Cancer incidence has increased in the last decades. Meanwhile, new and costly intravenous chemotherapy (CT) drugs are added to current treatment options. Cost of chemotherapy is not restricted to drugs themselves, and some of the equipment used for infusion can impact the final value. CT can be administered on simple IV lines ...

Diagnosis and Treatment Patterns for Non-Small Cell Lung Cancer (NSCLC) Within the Brazilian Private Healthcare System (PHS)

Abstract

OBJECTIVES: There is limited data on the prevalence, rate of mutations, and patterns of treatment for Non-Small Cell Lung Cancer (NSCLC) in a “real-world” setting in Brazil. The aim of this retrospective observational study was to evaluate the above-mentioned aspects from the private healthcare system’s (PHS) perspective in the ...