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A Systematic Review Of Health Economic Studies On Bipolar Disorder Type I In The United States

Abstract

Bipolar disorder (BD) is a recurrent chronic disorder characterized by fluctuations in mood state and energy. Bipolar disorder type I (BD-I) is a chronic and severe mental illness in which depressive episodes are typical, but not necessary for diagnosis. Although effective therapies are available, treatment rates remain low maintaining BD among the top 20 leading causes of disability worldwide surpassing asthma, myocardial infarction, dementia and infectious diseases. Several factors collaborate to increase the personal and economic burden of this illness: early age of onset, high incidence of comorbidities and substance abuse, steep risk of suicide, high relapse rates and poor adherence to treatment. The main objective was to identify, describe and critically assess health economic studies in BD-I in the United States during the last ten years and provide recommendations for future researchers.

Keywords

Bipolar disorder; type I; United States.

How to cite

Greene M, Clark OAC, Piedade A, Lemmer T, Hartry A. A Systematic Review Of Health Economic Studies On Bipolar Disorder Type I In The United States.  ISPOR USA; Boston: ISPOR; 2017.