Filtrar

Publicações

The Burden Of Acute Coronary Syndrome For The Brazilian Supplementary Health System

Abstract

To estimate the Brazilian supplementary health system costs of acute coronary syndrome (ACS), considering direct costs under the private payer perspec- tive. METHODS: Retrospective transactional-level data collection about hospitaliza- tion costs based on claims data from a private payer perspective. Data were collected ...

Budgetary Impact Of Oral Chemotherapy In Brazil: A Real World Data Analysis From The Private Payers’ Perspective

Abstract

In Brazil, health insurance companies (HIC) must, according to the law, offer coverage for intravenous (IVChem) antineoplastic drugs. The obligation to pay for oral drugs (OChem) was effective only after January 2014. Our goal was to evaluate the incremental costs and budgetary impact of the incorporation of OChem, using ...

Targeted therapy in triple-negative metastatic breast cancer: a systematic review and meta-analysis

Abstract

To perform a systematic review and meta-analysis of randomized controlled trials that compared the efficacy of targeted therapy to conventional chemotherapy (CT) in patients with metastatic triple-negative breast cancer (TNBC). METHODS: Several databases were searched, including Medline, Embase, LILACS, and CENTRAL. The ...

Amino Acid Formula As A First-Line Diagnosis Tool In Infants With Cow’s Milk Allergy (Cma): A Cost-Effectiveness Analysis Under The Brazilian Public Health Care System Perspective

Abstract

Cow’s milk allergy (CMA) is the main cause of food allergy in infants, resulting in life-threatening events such as anaphylaxis, impairment in growth and quality of life. CMA symptoms are also related to other diseases, making the differential diagnosis crucial for an earlier effective treatment, avoiding waste of ...

Burden of Drug Waste in Oncology: Optimization of Resource Use

Abstract

Minimizing waste of the use of drugs allows optimization of available resources in a scarce environment. Grouping patients may be an alternative to reduce drug waste in oncology. The aim of this study is to evaluate the economic impact of streamlined form of dispensation and percentage of drug wastage of the total drug ...

Intermittent versus continuous androgen deprivation for locally advanced, recurrent or metastatic prostate cancer: a systematic review and meta-analysis

Abstract

Prostate cancer is the most common cancer in older men in the United States (USA) and Western Europe. Androgen deprivation (AD) constitutes, in most cases, the first-line of treatment for these cases. The negative impact of CAD in quality of life, secondary to the adverse events of sustained hormone deprivation, plus the ...

Souvenaid® For The Dietary Management Of Mild Alzheimer’s Disease: 5-Year Budget Impact Analysis (BIA) From The Brazilian Public Payer Perspective (SUS)

Abstract

Souvenaid® is a medical food - an enriched nutritional formula - that contains specific nutrients reported to be deficient in patients with Alzheimer’s Disease (AD) and that are important in cognitive function, synapse formation and function. Clinical studies demonstrate that dietary management with Souvenaid® for 12 ...

Transcatheter Aortic Valve Implantation for the Treatment of Severe Aortic Valve Stenosis in Inoperable Patients under the Perspective of the Brazilian Private Healthcare System – Cost-Effectiveness Analysis

Keywords

TAVI; Transcatheter Aortic Valve Implantation or Implante de Valva Aortica Transcateter; Aortic Stenosis or Estenose Aortica; Cost-Effectiveness Analysis or Analise de Custo Efetividade; Private Healthcare System or Sistema de Saúde Privado; Health insurance company or Plano de Saude or ...

Cost-effectiveness of Sapien® transcatheter aortic valve for severe symptomatic aortic stenosis in inoperable patients in the Brazilian public health care system

Abstract

OBJECTIVES: Aortic stenosis is the most common valvular heart disease in the elderly - it is estimated that its prevalence is up to 5% in individuals over 75 years. Its standard treatment is surgical valve replacement; however the surgical risk is very high for patients with advanced age and with the association of ...

Hypofractionated external-beam radiation therapy (HEBRT) versus conventional external-beam radiation (CEBRT) in patients with localized prostate cancer: a systematic review and meta-analysis

Abstract

BACKGROUND: The purpose of this work was to conduct a systematic review and meta-analysis of all randomized controlled trials comparing the efficacy and side effect profile of hypofractionated versus conventional external-beam radiation therapy for prostate cancer. METHODS: Several databases were searched, including ...