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Impact of Indiscriminate Use of Pump Infusion Sets (PIS) on the Cost of Chemotherapy Treatments: a Cost-Minimization Study

Abstract

OBJECTIVES: Cancer incidence has increased in the last decades. Meanwhile, new and costly intravenous chemotherapy (CT) drugs are added to current treatment options. Cost of chemotherapy is not restricted to drugs themselves, and some of the equipment used for infusion can impact the final value. CT can be administered on simple IV lines ...

Diagnosis and Treatment Patterns for Non-Small Cell Lung Cancer (NSCLC) Within the Brazilian Private Healthcare System (PHS)

Abstract

OBJECTIVES: There is limited data on the prevalence, rate of mutations, and patterns of treatment for Non-Small Cell Lung Cancer (NSCLC) in a “real-world” setting in Brazil. The aim of this retrospective observational study was to evaluate the above-mentioned aspects from the private healthcare system’s (PHS) perspective in the ...

Real World Data on Colony-Stimulating factors (CSF) in Oncology: Patterns of Use in Brazil

Abstract

Incorrect use of colony stimulating factors (CSF) can add unnecessary cost to cancer treatments and adverse events to patients. We conducted an epidemiological study to assess the correlation between CSF use recommendations issued by the Brazilian Regulatory Agency of Health (ANS) and technical recommendations stated by international guidelines. We ...

Type II Diabetes Prevalence, Hypoglycemia Episodes and HBA1C Control in Brazil

Abstract

The prevalence of diabetes mellitus has increased in recent decades, with approximately 90% of diabetic patients currently worldwide classified as type 2 diabetes mellitus (DM2). In 2030, WHO projects 366 million adults will have DM2 worldwide. Emerging markets are strongly affected by the increase in DM2. In fact, ...

Recent Hypoglycemia Episodes Are Associated With Poorer Quality of Life, Healthcare Resource Use, and Work Impairment Among Patients With Type II Diabetes in Brazil

Abstract

Hypoglycemic episodes (HE) are an important problem in diabetes mellitus type II (DM2) and are associated with increased mortality and decreased health-related quality of life (HRQoL). Several comorbidities, such as cardiovascular and neurologic events, are associated withHE and represent an important complication related to DM2. Moreover, ...

Biosimilar Trials: Patient Recruitment and Barriers in Brazil

Abstract

Biologics and biosimilar drugs represented a hallmark in drug development.  Along with the requirements of similarity, even after comparability exercise, a phase 3, pivotal trial, head-to-head trial is required to show that there are no differences between reference and biosimilar drugs. Much has been ...

The Association Between Tolerability Issues and Health Outcomes Among Patients With HCV in Brazil

Abstract

OBJECTIVES: The hepatitis C virus (HCV) is one of the most common blood-borne viral illnesses in Brazil and associated with various sequelae including cirrhosis and hepatocellular carcinoma. Treatment can be effective but also carries the risk of tolerability issues. The current study assessed the prevalence of tolerability issues among HCV ...

Standards of Surgical Materials Usage in Anterior Cruciate Ligament (ACL) Surgery in Brazil Under the Perspective of the Private Health Care System

Abstract

To describe the standards of the surgical approach, in terms of material usage and costs, for anterior cruciate ligament (ACL) injury under the Brazilian Private Healthcare System (PHS) as well as evaluate some epidemiological features on the patients suffering from this injury. METHODS: A cross-sectional study using Evidências-Kantar Health ...

Hospitalization Costs of Type 2 Diabetes Mellitus (T2DM) Patients in a Public Hospital in Brazil

Abstract

Diabetes is considered an outpatient care condition, manageable in the primary care setting, but which complications may lead to hospitalization. There is limited data on the costs of patients hospitalized due to diabetes in Brazil. We aimed to estimate the percentage of type-2 diabetes mellitus (T2DM) patients who were hospitalized and the ...

A Streamlined Approach to Ethics review in Brazil

Abstract

Clinical trials must be reviewed by an independent ethics committee (IRB) besides having scientific validity and favorable benefit risk ratio. Different approaches are available worldwide for research ethics review. Review may occur at institutional level, at both national and institutional level, and at a regional level. Furthermore, there are ...