According to a study from the University of New York, the risk of developing melanoma has increased 30-fold during the last 80 years, especially due to elevate sun exposure, which accounts for 65% of all cases. Metastatic melanoma (MM) is a disease with a somber prognosis and mean overall survival of 8 to 18 months (1). ...
Eight risk factors (alcohol use, tobacco use, high blood pressure, high body mass index, high cholesterol levels, high blood glucose levels, low fruit and vegetable intake, and physical inactivity) account for 61% of cardiovascular deaths (1). Non-communicable diseases (NCDs) are the main sources of disease burden in ...
Non-communicable diseases (NCDs) are the main sources of disease burden in Brazil. In 2007, about 72% of all deaths in Brazil were attributable to NCDs (cardiovascular diseases, chronic respiratory illnesses, diabetes, cancer, and others, including kidney conditions). Principal among the chronic disorders were neuropsychiatric disorders ...
Over one sixth of the illnesses and disabilities suffered worldwide are caused by vector- -borne diseases, and more than half the world’s population is estimated to be at risk for these diseases currently. 1 Aedes aegypti is one of the main vectors, responsible for transmitting four diseases that had major outbreaks ...
Microcephaly is a condition in which a baby’s head is smaller when compared with other babies of the same age and sex. Head size is important to monitor a child’s brain growth, and microcephaly can affect the child’s development and lead to a series of sequelae, which can be extremely serious depending on the ...
Cancer is one of the main causes of death worldwide with a high economic burden, especially for low and middle-income countries.1, 2 In Brazil, there is an increasing trend in cancer mortality and estimates of even higher numbers in the future.3 In this scenario, real-world studies are necessary to help understand cancer ...
Orthognathic surgery is used to correct discrepancies (such as maxillary, mandibular, sagittal, vertical and transversal ones) in the skeletal structures of the face. The procedure consists of a series of osteotomies to allow the correct repositioning of facial bones, which are then afxed in position by titanium plates ...
A despeito do aumento global da prevalência da obesidade, nenhum país no mundo implementou de maneira satisfatória caminhos para orientação e condu- ção de pacientes obesos que buscam tratamento. No Brasil esta realidade se reflete dramaticamente tanto no sistema público, quanto no sistema de saúde suplementar ...
The prevalence of chronic pain has been estimated between 12% - 30% in the general population across European countries (1). In Colombia, a transversal cohort study found a prevalence of chronic pain in 31% of adult population in Caldas (n=1008) (3) and a population-based cross-sectional study found a prevalence of 33.9% ...
OBJECTIVES:: Safety and efficacy of protease inhibitors for chronic hepatitis C (CHC) treatment were showed previously, however, the Brazilian population has been poorly represented in these investigations. Therefore, this study aimed to describe the effectiveness in terms of rapid virological response (RVR) and ...