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Erythropoietin, uncertainty principle and cancer related anaemia

Abstract

This study was designed to evaluate if erythropoietin (EPO) is effective in the treatment of cancer related anemia, and if its effect remains unchanged when data are analyzed according to various clinical and methodological characteristics of the studies. We also wanted to demonstrate that cumulative meta-analysis (CMA) ...

Erythropoietin, uncertainty principle and cancer related anemia

Abstract

This study was designed to evaluate if erythropoietin (EPO) is effective in the treatment of cancer related anemia, and if its effect remains unchanged when data are analyzed according to various clinical and methodological characteristics of the studies. We also wanted to demonstrate that cumulative meta-analysis (CMA) ...

Searching the Literatura Latino Americana e do Caribe em Ciencias da Saude (LILACS) database improves systematic reviews

Abstract

An unbiased systematic review (SR) should analyse as many articles as possible in order to provide the best evidence available. However, many SR use only databases with high English-language content as sources for articles. Literatura Latino Americana e do Caribe em Ciencias da Saude (LILACS) indexes 670 journals from ...

Quality and methods of developing practice guidelines

Abstract

It is not known whether there are differences in the quality and recommendations between evidence-based (EB) and consensus-based (CB) guidelines. We used breast cancer guidelines as a case study to assess for these differences. METHODS: Five different instruments to evaluate the quality of guidelines were identified by a ...

Database for health outcomes and quality of randomized trials in multiple myeloma

Keywords

Databases or Bases de Dados; Multiple Myeloma or Mieloma Múltiplo; Randomized Controlled Trials or Estudos Randomizados Controlados; 

How to cite this article

Djulbegovic B, Clark OAC, Hozo I. Database for ...

Update 2002: Bisphosphonates in multiple myeloma

Abstract

Multiple myeloma is a disease characterized by the neoplastic proliferation of a clone of plasma cells that can lead to bone destruction. Bisphosphonates are specific inhibitors of osteoclastic activity. Therefore, there is a pharmacological basis for their use in multiple myeloma. However, the exact clinical role of ...

Use and indications of hormonal blockers in prostate cancer

Keywords

Cancer or Câncer; Hormone Therapy or Terapia Hormonal; Hormonal Blockers or Bloqueio Hormonal; Prostate Cancer or Câncer de Próstata; Guidelines or Diretrizes Clínicas;

How to cite this article

Is clinical research still too haphazard?

Abstract

Sarah Ramsay reports, in her July 21 news item, the death of a young volunteer in the Johns Hopkins study on hexamethonium, from pulmonary complications believed to be due to adverse effects of l g of the drug administered by inhalation. We believe that the case reflects features of physiological and clinical research ...

Cochrane reviews must use LILACS as source of articles.

Abstract

LILACS is a triple language database edited by BIREME and PAHO in Sao Paulo, Brazil, with interfaces in Spanish, Portuguese and English. This database indexes more than 670 medical journals in Latin America and Caribbean. Only 40 of these are indexed also in MEDLINE. So, LILACS is a unique source of scientific ...

Improving Retrieval of Clinical Trials in the LILACS Database (part II)

Abstract

The aim of this study was to identify and analyse RCTs and CCTs in the LILACS database (Latin American and Caribbean Health Science Information Database). The LILACS database indexes 670 journals in the region, with 260,945 records and abstracts in English, Portuguese or Spanish. Only 41 overlap these in the ...