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Advanced testicular cancer

Keywords

Testicular Cancer or Cancer de Testiculo; Guidelines or Diretrizes Clínicas; Chemoterapy or Quimioterapia; Radiotherapy or Radioterapia; 

How to cite this article

Clark O, Pompeo AC, Bretas FF, Sadi MV, ...

Hormone treatment for prostate cancer

Keywords

Hormonal Blockers or Bloqueio Hormonal; Hormone Therapy or Terapia Hormonal; Prostate Cancer or Câncer de Próstata; Guidelines or Diretrizes Clínicas; 

How to cite this article

Ferreira U, Clark O, Pompeo ...

Localized testicular cancer

Keywords

Testicular Cancer or Cancer de Testiculo; Surgery or Cirurgia; Chemoterapy or Quimioterapia; Radiotherapy or Radioterapia; Guidelines or Diretrizes Clínicas;

How to cite this article

Pompeo AC, Bretas FF, ...

Amifostine reduces side effects and improves complete response rate during radiotherapy: results of a meta-analysis

Abstract

PURPOSE: To evaluate the efficacy of amifostine in diminishing radiotherapy side effects and whether or not it protects the tumor. METHODS AND MATERIALS: We performed a systematic review and meta-analysis of 14 included randomized controlled trials, comprising 1451 patients, comparing the use of radiotherapy vs. ...

Economic impact of an evidence based approach to tumor marker requests in a health plan in Brazil

Abstract

Background: Many physicians recommend routine measurement of tumor markers to their patients as screening tests or for monitoring responses to anti-neoplastic treatment. The use of diagnostic tests without evidence to support them may cause an increase in costs and often unnecessary anxieties on patients, leading to ...

Evidence-based urology: why is it important?

Abstract

Do momento em que você se levanta pela manhã, às 6:00 horas, até quando retorna, por volta das 22:00 horas, tendo saído sem tomar café, operado a manhã toda, almoçado um sanduíche, comparecido a três reuniões de departamento e atendido a um consultório lotado, 1.168 novos artigos terão sido incluídos no ...

Evidence based audit in oncology: analyses of three health plans in Brazil

Abstract

Background: The costs of oncology are among the highest in most health systems. The use of therapies based in low quality studies is not uncommon and have a high economic impact. In Brazil, the health plans (HP) are, by law, not required to cover experimental therapies.

Objective: ...

Colony-stimulating factors for chemotherapy-induced febrile neutropenia: a meta-analysis of randomized controlled trials

Abstract

PURPOSE: Current treatment for febrile neutropenia (FN) includes hospitalization for evaluation, empiric broad-spectrum antibiotics, and other supportive care. Clinical trials have reported conflicting results when studying whether the colony-stimulating factors (CSFs) improve outcomes in patients with FN. This Cochrane ...

Localized prostate cancer

Keywords

Cancer or Câncer; Prostate Cancer or Câncer de Próstata; Surgery or Cirurgia; Radiotherapy or Radioterapia; Guidelines or Diretrizes Clínicas; 

How to cite this article

Ferreira U, Netto Jr NR, Koff ...

Use of re-randomized data in meta-analysis

Abstract

BACKGROUND: Outcomes collected in randomized clinical trials are observations of random variables that should be independent and identically distributed. However, in some trials, the patients are randomized more than once thus violating both of these assumptions. The probability of an event is not always the same when a ...